Mutations affecting thymus organogenesis in Medaka, Oryzias latipes
نویسندگان
چکیده
منابع مشابه
Mutations affecting thymus organogenesis in Medaka, Oryzias latipes
The thymus is an organ for T lymphocyte maturation and is indispensable for the establishment of a highly developed immune system in vertebrates. In order to genetically dissect thymus organogenesis, we carried out a large-scale mutagenesis screening for Medaka mutations affecting recombination activating gene 1 (rag1) expression in the developing thymus. We identified 24 mutations, defining at...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2004
ISSN: 0925-4773
DOI: 10.1016/j.mod.2004.03.020